A clinical study to determine the threshold of bronchodilator response for diagnosing asthma in Chinese children.

ABSTRACT:

Background

There is few objective, clinically feasible and inexpensive test for diagnosing childhood asthma. We want to find an ideal way to solve it.

Methods

The control group was 301 non-asthmatic children, and the asthma group was 286 asthmatic children. The asthmatic children were divided into three groups according to the severity of their disease. Pre- and post-bronchodilator spirometer tests were performed, and the main spirometer parameters were compared. The bronchodilator response (BDR) [BDR is used to determine the reversibility of airway obstruction by measuring the changes of forced expiratory volume in the first second (FEV₁) before and after inhalation of bronchodilators] was then determined, and the optimal threshold of BDR for diagnosing childhood

SUBMITTER: Kang XH 

PROVIDER: S-EPMC6872507 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature