Type 1, 2, and 1/2-Hybrid IncC Plasmids From China.

ABSTRACT: A collection of 11 IncC plasmids from China were fully sequenced herein and compared with reference plasmids pR148 and pR55. These 13 plasmids could be assigned into three different subgroups: type 1, type 2, and type 1/2 hybrid. Type 1/2-hybrid plasmids most likely emerged from homologous recombination between type 1 and type 2 plasmids. Different IncC plasmids had evolved to acquire quite different profiles of accessory modules and thus different collections of resistance genes. The accessory resistance modules included not only the bla _CMY-carrying region, the ARI-A island, and the ARI-B island, but also various additional kinds of resistance islands such as the bla _CTX-M-carrying regions and the MDR regions. Insertion of accessory modules was sometim

SUBMITTER: Cheng Q 

PROVIDER: S-EPMC6872532 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature