Tidal Volume Estimation during Helmet Noninvasive Ventilation: an Experimental Feasibility Study.

ABSTRACT: We performed a bench (BS) and human (HS) study to test the hypothesis that estimation of tidal volume (V_T) during noninvasive helmet pressure support ventilation (nHPSV) would be possible using a turbine driven ventilator (TDV) coupled with an intentional leak single-limb vented circuit. During the BS a mannequin was connected to a lung simulator (LS) and at different conditions of respiratory mechanics, positive end expiratory pressure (PEEP) levels and leaks (30, 50 and 80 L/min). All differences were within the 95% limits of agreement (LoA) in all conditions in the Bland-Altman plot. The overall bias (difference between V_T measured by TDV and LS) was 35 ml (95% LoA 10 to 57 ml), 15 ml (95% LoA -40 to 70 ml), 141 ml (95% LoA 109 to 173 ml) in the normal, restrictive

SUBMITTER: Cortegiani A 

PROVIDER: S-EPMC6872634 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature