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New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata.


ABSTRACT: Two hitherto unknown iboga-type indole alkaloids, namely (3R)-7,19-di-epi-3-methoxytabernoxidine (1) and (3R,19R)-19-hydroxy-3-(2-oxopropyl)voacangine (2), together with eight known alkaloids (3-10), were isolated from the twigs and leaves of Tabernaemontana divaricata. Their structures were established on the basis of spectroscopic data interpretation, single crystal X-ray diffraction analysis and circular dichroism spectrum.

SUBMITTER: Li XM 

PROVIDER: S-EPMC6872691 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata.

Li Xiang-Mei XM   Jiang Xian-Jun XJ   Wei Guo-Zhu GZ   Ren Li-Hua LH   Wang Li-Xia LX   Cheng Xue-Lian XL   Wang Fei F  

Natural products and bioprospecting 20191114 6


Two hitherto unknown iboga-type indole alkaloids, namely (3R)-7,19-di-epi-3-methoxytabernoxidine (1) and (3R,19R)-19-hydroxy-3-(2-oxopropyl)voacangine (2), together with eight known alkaloids (3-10), were isolated from the twigs and leaves of Tabernaemontana divaricata. Their structures were established on the basis of spectroscopic data interpretation, single crystal X-ray diffraction analysis and circular dichroism spectrum. ...[more]

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