An atypical case of acute posterior multifocal placoid pigment epitheliopathy with recurrent strokes.

ABSTRACT:

Purpose

To report an atypical case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) with central nervous system (CNS) vasculitis and recurrent strokes.

Observations

A 57 year-old female presented with APMPPE after a febrile illness and rash. She developed an acute infarct on magnetic resonance imaging. Computed tomography angiography of the cerebral vasculature was normal. Cerebrospinal fluid (CSF) analysis and an extensive serum lab workup were also unremarkable. She was treated with high-dose corticosteroids and eventually transitioned to methotrexate. A month after being on treatment she developed a second stroke. A cerebral angiogram was obtained and did not show evidence of CNS vasculitis. The methotrexate was eventually stopped and the prednisone w

SUBMITTER: Berger E 

PROVIDER: S-EPMC6872853 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature