Stroop-related cerebellar and temporal activation is correlated with negative affect and alcohol use disorder severity.

ABSTRACT: Impairment in cognitive control in alcohol use disorder (AUD) contributes to difficulty controlling alcohol use and, in many populations, difficulties with emotion regulation. However, the most reliable and robust marker of clinically-relevant deficits in cognitive control in AUD is unclear. Our aims were to measure relationships between BOLD signal during a Stroop task and AUD severity and change in BOLD signal and change in drinking over three weeks. We also aimed to explore the relationships between BOLD signal and subjective negative affect. Thirty-three individuals with AUD underwent a multisensory Stroop task during functional magnetic resonance imaging (fMRI), as well as a battery of neuropsychological tests and self-report assessments of negative affect and AUD severity. Greater ac

SUBMITTER: Wilcox CE 

PROVIDER: S-EPMC6872926 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature