Transcriptomic and Single-Cell Analysis of the Murine Parotid Gland.

ABSTRACT: The salivary complex of mammals consists of 3 major pairs of glands: the parotid, submandibular, and sublingual glands. While the 3 glands share similar functional properties, such as saliva secretion, their differences are largely based on the types of secretions they produce. While recent studies have begun to shed light on the underlying molecular differences among the glands, few have examined the global transcriptional repertoire over various stages of gland maturation. To better elucidate the molecular nature of the parotid gland, we have performed RNA sequencing to generate comprehensive and global gene expression profiles of this gland at different stages of maturation. Our transcriptomic characterization and hierarchical clustering analysis with adult organ RNA sequencing data set

SUBMITTER: Oyelakin A 

PROVIDER: S-EPMC6873284 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature