Characteristics and outcomes of antiretroviral-treated HIV-HBV co-infected patients in Canada?

ABSTRACT: BACKGROUND:Hepatitis B (HBV) and Human Immunodeficiency Virus (HIV) share common risk factors for exposure. Co-infected patients have an increased liver-related mortality risk and may have accelerated HIV progression. The epidemiology and demographic characteristics of HIV-HBV co-infection in Canada remain poorly defined. We compared the demographic and clinical characteristics and factors associated with advanced hepatic fibrosis between HIV and HIV-HBV co-infected patients. METHODS:A retrospective cohort analysis was conducted using data from the Canadian Observational Cohort (CANOC) Collaboration, including eight sites from British Columbia, Quebec, and Ontario. Eligible participants were HIV-infected patients who initiated combination ARV between January 1, 2000 and December 14, 2014.

SUBMITTER: Rana U 

PROVIDER: S-EPMC6873547 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature