Genetic influences on treatment-seeking for common mental health problems in the UK biobank.

ABSTRACT: The majority of those who experience clinical anxiety and/or depressive symptoms in the population do not receive treatment. Studies investigating inequalities in treatment outcomes rarely consider that individuals respond differently to their experience of the environment. Much of our environment is under genetic influence, via our behaviour, whereby individuals actively select their experiences. If genes influence who seeks and receives treatment, selection bias will confound genomic studies of treatment response. Furthermore, if some individuals are at high genetic risk of needing but not commencing treatment, then greater efforts could be made to engage them. The role of common genetic variation on four lifetime treatment-seeking behaviours (treatment-seeking, treatment-receipt, self-h

SUBMITTER: Rayner C 

PROVIDER: S-EPMC6873796 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature