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Human Infection with Orf Virus and Description of Its Whole Genome, France, 2017.


ABSTRACT: Zoonotic transmission of parapoxvirus from animals to humans has been reported; clinical manifestations are skin lesions on the fingers and hands after contact with infected animals. We report a human infection clinically suspected as being ecthyma contagiosum. The patient, a 65-year-old woman, had 3 nodules on her hands. She reported contact with a sheep during the Aïd-el-Fitr festival in France during 2017. We isolated the parapoxvirus orf virus from these nodules by using a nonconventional cell and sequenced the orf genome. We identified a novel orf virus genome and compared it with genomes of other orf viruses. More research is needed on the genus Parapoxvirus to understand worldwide distribution of and infection by orf virus, especially transmission between goats and sheep.

SUBMITTER: Andreani J 

PROVIDER: S-EPMC6874271 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Human Infection with Orf Virus and Description of Its Whole Genome, France, 2017.

Andreani Julien J   Fongue Jessica J   Bou Khalil Jacques Y JY   David Laurene L   Mougari Saïd S   Le Bideau Marion M   Abrahão Jonatas J   Berbis Philippe P   La Scola Bernard B  

Emerging infectious diseases 20191201 12


Zoonotic transmission of parapoxvirus from animals to humans has been reported; clinical manifestations are skin lesions on the fingers and hands after contact with infected animals. We report a human infection clinically suspected as being ecthyma contagiosum. The patient, a 65-year-old woman, had 3 nodules on her hands. She reported contact with a sheep during the Aïd-el-Fitr festival in France during 2017. We isolated the parapoxvirus orf virus from these nodules by using a nonconventional ce  ...[more]

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