Human astrovirus infection associated with encephalitis in an immunocompetent child: a case report.

ABSTRACT:

Background

Until today, classic human astroviruses have not been associated with central nervous system infections in immunocompetent patients.

Case presentation

A 16-month-old Caucasian girl presented with repetitive generalized seizures with a 4-day history of watery diarrhea, which had already gradually improved. Initially, the prolonged seizures ceased after systemic midazolam treatment and were thought to be fever associated. However, her mental status remained altered, and after seizure recurrence, she was transferred to our pediatric intensive care unit. Seizure control was achieved by a combination of high-dose levetiracetam and phenobarbital, but she remained unconscious. An electroencephalogram at this time revealed generalized high voltage theta activity. All labo

SUBMITTER: Koukou G 

PROVIDER: S-EPMC6874811 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature