Incomer, a DD36E family of Tc1/mariner transposons newly discovered in animals.

ABSTRACT:

Background

The Tc1/mariner superfamily might represent the most diverse and widely distributed group of DNA transposons. Several families have been identified; however, exploring the diversity of this superfamily and updating its classification is still ongoing in the life sciences.

Results

Here we identified a new family of Tc1/mariner transposons, named Incomer (IC), which is close to, but distinct from the known family DD34E/Tc1. ICs have a total length of about 1.2 kb, and harbor a single open reading frame encoding a ~ 346 amino acid transposase with a DD36E motif and flanked by short terminal inverted repeats (TIRs) (22-32 base pairs, bp). This family is absent from prokaryotes, and is mainly distributed among vertebrates (141

SUBMITTER: Sang Y 

PROVIDER: S-EPMC6875036 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature