Comparison of self-reported female condom failure and biomarker-confirmed semen exposure.

ABSTRACT:

Objective

To investigate whether rates of self-reported Woman's Condom (WC) clinical failure and semen exposure from a functionality study are comparable to results from a contraceptive efficacy substudy.

Study design

We structured our comparative analysis to assess whether functionality studies might credibly supplant contraceptive efficacy studies when evaluating new female condom products. Couples not at risk of pregnancy in the functionality (breakage/slippage/invagination/penile misdirection) study and women in the contraceptive efficacy study completed condom self-reports and collected precoital and postcoital vaginal samples for up to four uses of the WC. Both studies used nearly identical self-report questions and the same self-sampling procedures and laboratory for

SUBMITTER: Walsh TL 

PROVIDER: S-EPMC6875637 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature