TS-GOEA: a web tool for tissue-specific gene set enrichment analysis based on gene ontology.

ABSTRACT:

Background

The Gene Ontology (GO) knowledgebase is the world's largest source of information on the functions of genes. Since the beginning of GO project, various tools have been developed to perform GO enrichment analysis experiments. GO enrichment analysis has become a commonly used method of gene function analysis. Existing GO enrichment analysis tools do not consider tissue-specific information, although this information is very important to current research.

Results

In this paper, we built an easy-to-use web tool called TS-GOEA that allows users to easily perform experiments based on tissue-specific GO enrichment analysis. TS-GOEA uses strict threshold statistical method for GO enrichment analysis, and provides statistical tests to improve the reliability of the analysi

SUBMITTER: Peng J 

PROVIDER: S-EPMC6876092 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature