Impact of Arteriovenous fistula creation on estimated glomerular filtration rate decline in Predialysis patients.

ABSTRACT:

Background

Arteriovenous fistula (AVF) is the vascular access of choice for patients on hemodialysis. Recent evidence suggests that AVF creation may slow estimated glomerular filtration rate (eGFR) decline. The study objective was to assess the impact of the AVF creation on eGFR decline, after controlling for key confounding factors.

Methods

This retrospective cohort study included adult patients followed in a single-center predialysis clinic between 1999 and 2016. Patients with a patent AVF were followed up to 2 years pre- and post-AVF creation. Estimated GFR trajectory was reported using linear mixed models adjusted for demographic characteristics, comorbidities and use of renin-angiotensin-aldosterone blockade.

Results

A total of 146 patients were studied with a me

SUBMITTER: Benard V 

PROVIDER: S-EPMC6876290 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature