Questionable utility of digoxin in left-ventricular assist device recipients: A multicenter, retrospective analysis.

ABSTRACT:

Background

While clinical experience with left ventricular assist devices (LVAD) continues to grow and evolve, little is known regarding the ongoing use of certain medications in this population. We sought to evaluate the utility of digoxin in LVAD recipients and its association with outcomes.

Methods

A total of 505 patients who underwent continuous-flow LVAD implantation at 5 centers from 2007-2015 were included. Patients were divided into 4 groups: not on digoxin at any time (ND; n = 257), received digoxin pre implant (PreD; n = 144), received digoxin pre and post implant (ContD; n = 55), and received digoxin only post implant (PostD; n = 49). Survival and all-cause readmission were compared between the 4 groups.

Results

There was no difference in survival at 1 year

SUBMITTER: Ahmed MM 

PROVIDER: S-EPMC6876793 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature