Indicators of mental disorders in UK Biobank-A comparison of approaches.

ABSTRACT:

Objectives

For many research cohorts, it is not practical to provide a "gold-standard" mental health diagnosis. It is therefore important for mental health research that potential alternative measures for ascertaining mental disorder status are understood.

Methods

Data from UK Biobank in those participants who had completed the online Mental Health Questionnaire (n = 157,363) were used to compare the classification of mental disorder by four methods: symptom-based outcome (self-complete based on diagnostic interviews), self-reported diagnosis, hospital data linkage, and self-report medication.

Results

Participants self-reporting any psychiatric diagnosis had elevated risk of any symptom-based outcome. Cohen's κ between self-reported diagnosis and symptom-based outcome

SUBMITTER: Davis KAS 

PROVIDER: S-EPMC6877131 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature