Retention of Alzheimer Disease Research Participants.

ABSTRACT:

Introduction

Participant retention is important to maintaining statistical power, minimizing bias, and preventing scientific error in Alzheimer disease and related dementias research.

Methods

We surveyed representative investigators from NIH-funded Alzheimer's Disease Research Centers (ADRC), querying their use of retention tactics across 12 strategies. We compared survey results to data from the National Alzheimer's Coordinating Center for each center. We used a generalized estimating equation with independent working covariance model and empirical standard errors to assess relationships between survey results and rates of retention, controlling for participant characteristics.

Results

Twenty-five (83%) responding ADRCs employed an average 42 (SD=7) retention tactics

SUBMITTER: Grill JD 

PROVIDER: S-EPMC6878201 | biostudies-literature | 2019 Oct-Dec

REPOSITORIES: biostudies-literature