Onychomadesis and potential association with HFMD outbreak in a kindergarten in Hubei province, China, 2017.

ABSTRACT:

Background

In 2017, an outbreak of onychomadesis occurred in kindergarten H, Hubei province, China. We investigated the field to learn about the magnitude and reason of the outbreak.

Methods

The case definition was that a child with onychomadesis or transverse ridging (Beau's line) in fingernails and toenails without previous traumatic or systemic disease in kindergarten H from Sep. 1st to Nov. 30th, 2017. A retrospective cohort study was carried out to analyze the epidemiological relationship between onychomadesis and the hand-foot-mouth disease (HFMD) in Primary Class #2, kindergarten H. We also performed a serological survey for neutralizing antibodies against coxsackie virus A6 (CVA6), coxsackie virus A10 (CVA10) among 15 cases and six healthy children in the kindergarte

SUBMITTER: Li D 

PROVIDER: S-EPMC6878681 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature