The ZJU index is a powerful surrogate marker for NAFLD in severely obese North American women.

ABSTRACT:

Introduction

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the western world and is highly associated with multiple cardiometabolic complications. The Zhejiang University (ZJU) index was first developed to predict NAFLD in Chinese populations, where it was shown to have better predictive value than other currently used indices. The aims of the present study were to 1) determine the diagnostic accuracy of ZJU index in identifying NAFLD in a well-phenotyped cohort of obese middle-aged American women and 2) compare its performance with other non-invasive indices for NAFLD identification.

Methods

To achieve this goal, we performed a retrospective analysis of a prospectively-collected cohort of participants enrolled in a weight loss trial f

SUBMITTER: Fu CP 

PROVIDER: S-EPMC6879170 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature