Bone material strength in normoglycemic and hyperglycemic black and white older adults.

ABSTRACT: This cross-sectional study assessed cortical bone properties via impact microindentation in adults with normoglycemia, prediabetes, and early-stage T2D. Bone material strength index was stable across the glycemia categories in whites but it declined in blacks. Blacks may be more susceptible than whites to impaired cortical bone properties in early diabetes.

Introduction

Individuals with long-standing type 2 diabetes (T2D) have altered cortical bone material properties as determined by impact microindentation. This cross-sectional study was done to determine whether altered cortical bone material properties could be detected in adults with prediabetes or early-stage T2D.

Methods

Men and postmenopausal women aged ≥ 50 years with no diabetes (50 white, 6 black), prediabetes (75

SUBMITTER: Dawson-Hughes B 

PROVIDER: S-EPMC6879849 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature