Quantitative assessment of Ki67 expression in correlation with various breast cancer characteristics and survival rate; cross sectional study.

ABSTRACT:

Background

Ki-67 is a cellular proliferative index that has variable expression during cell cycle. The absence of Ki-67 in the quiescent tissues and its expression in the proliferating cells had linked its possible role in the proliferative capacity of the tissues.

Materials and methods

This retrospective study included 314 patients with breast cancer who underwent various types of breast surgeries. Analyzed was done to find any possible correlation between the level of Ki67 and various patient and tumor characteristics and the survival rates.

Results

The mean age was 48.73 years, the overall survival was 30.77 months, 90.8% of the patients were alive and 8.3% died from breast cancer. In 85.67% no recurrence was reported and 5% had local and axillary recurrences, the

SUBMITTER: Mohammed AA 

PROVIDER: S-EPMC6880115 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature