Nature and consequences of interactions between Salmonella enterica serovar Dublin and host cells in cattle.

ABSTRACT: Salmonella enterica is a veterinary and zoonotic pathogen of global importance. While murine and cell-based models of infection have provided considerable knowledge about the molecular basis of virulence of Salmonella, relatively little is known about salmonellosis in naturally-affected large animal hosts such as cattle, which are a reservoir of human salmonellosis. As in humans, Salmonella causes bovine disease ranging from self-limiting enteritis to systemic typhoid-like disease and exerts significant economic and welfare costs. Understanding the nature and consequences of Salmonella interactions with bovine cells will inform the design of effective vaccines and interventions to control animal and zoonotic infections. In calves challenged orally with S. Dublin expressing green fluorescen

SUBMITTER: Vohra P 

PROVIDER: S-EPMC6880441 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature