Mortality patterns in long-term survivors of childhood or adolescent central nervous system tumour in Sweden.

ABSTRACT:

Purpose

A growing number of young patients with central nervous system (CNS) tumour survived for more than five years. However, these long-term survivors might be at risk of multiple late effects thus leading to a higher risk of late mortality. We aimed to explore the risk of late mortality and the pattern of mortality among long-term survivors of childhood or adolescent CNS tumour.

Methods

We identified 5-year survivors with childhood or adolescent CNS tumour before age 20 years through the Swedish Cancer Registry. Five controls were randomly matched for each patient to generate the reference group. We retrieved information about death via Cause of Death Register. We calculated the absolute excess risk (AER) of death and the hazard ratio (HR) of death using Cox proportional

SUBMITTER: Huang W 

PROVIDER: S-EPMC6881431 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature