Classifying Mood Symptom Trajectories in Adolescents With Bipolar Disorder.

ABSTRACT:

Objective

The Course and Outcome of Bipolar Youth study found that children and adolescents with bipolar spectrum disorders followed 1 of 4 distinct mood trajectories over 8 years of follow-up, with as many as 25% of participants showing a predominantly euthymic course. We evaluated whether similar patterns of illness course are observed in adolescents with bipolar I and II disorder who participated in a 2-year clinical trial.

Method

A total of 144 adolescents with bipolar I or II disorder, identified shortly after a mood episode, were assessed over a 2-year period. Participants were randomly assigned to one of 2 psychosocial family treatments during the first 9 months of the study, and pharmacotherapy was provided throughout the 2 years. Using latent class growth analyses,

SUBMITTER: Weintraub MJ 

PROVIDER: S-EPMC6881540 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature