Proteomic features characterization of Hymenoptera venom allergy.

ABSTRACT:

Background

Hymenoptera venom allergy is one of the most frequent causes of anaphylaxis. In its most severe form, the reaction to wasp and honey bee stings may be life-threatening. Therefore, immediate and proper diagnosis of venom allergy and implementation of suitable therapy are extremely important. Broadening the knowledge on the mechanism of the allergic reaction may contribute to the improvement of both diagnostic and treatment methods. Thus, this study aimed to discover changes in protein expression in serum of patients allergic to Hymenoptera (wasp and honeybee) venom and to point out proteins and peptides involved in the allergic inflammation.

Methods

Serum proteomic patterns typical to allergic patients and healthy volunteers were obtained with MALDI-T

SUBMITTER: Matuszewska E 

PROVIDER: S-EPMC6881982 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature