A comparison of clinical paediatric guidelines for hypotension with population-based lower centiles: a systematic review.

ABSTRACT: BACKGROUND:Different definitions exist for hypotension in children. In this study, we aim to identify evidence-based reference values for low blood pressure and to compare these with existing definitions for systolic hypotension. METHODS:We searched online databases until February 2019 (including MEDLINE, EMBASE, Web of Science) using a comprehensive search strategy to identify studies that defined age-related centiles (first to fifth centile) for non-invasive systolic blood pressure in healthy children < 18 years. Existing cut-offs for hypotension were identified in international guidelines and textbooks. The age-related centiles and clinical cut-offs were compared and visualized using step charts. RESULTS:Fourteen studies with population-based centiles were selected, of which 2 addressed

SUBMITTER: Hagedoorn NN 

PROVIDER: S-EPMC6882047 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature