Impact of early antiretroviral treatment on sexual behaviour: a randomised comparison.

ABSTRACT:

Background

Antiretroviral treatment (ART) reduces HIV infectiousness but the effect of early ART on sexual behaviour is unclear.

Methods

We assessed, within the START randomized trial that enrolled HIV-positive adults with CD4 cell count greater than 500 cells/μl, the effect of early (immediate) versus deferred ART on: condomless sex with HIV-serodifferent partners (CLS-D); all condomless sex (CLS); HIV transmission-risk sex (CLS-D-HIV risk, defined as CLS-D and: not on ART or started ART <6 months ago or viral load greater than 200 copies/ml or no viral load in past 6 months), during 2-year follow-up. Month-12 CLS-D (2010-2014) was the primary outcome.

Results

Among 2562 MSM, there was no difference between immediate and deferred arms in CLS-D at month 12 [12.6 versu

SUBMITTER: Lampe FC 

PROVIDER: S-EPMC6882545 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature