Cannabis Use and Markers of Systemic Inflammation: The Coronary Artery Risk Development in Young Adults Study.

ABSTRACT:

Background

It is unclear whether cannabis use in humans plays a role in the regulation of inflammatory responses. This study aimed to examine cannabis-attributable immunomodulation as manifested in levels of fibrinogen, C-reactive protein (CRP), and interleukin-6 (IL-6).

Methods

The Coronary Artery Risk Development in Young Adults (CARDIA) study is a cohort of 5115 African-American and Caucasian males and females enrolled in 1985-1986, and followed up for over 25 years, with repeated measures of cannabis use. Fibrinogen levels were measured at year 5, year 7, and year 20, CRP levels were measured at year 7, year 15, year 20, and year 25, and IL-6 levels were measured at year 20. We estimated the association of cannabis use and each biomarker using generalized estimating equa

SUBMITTER: Alshaarawy O 

PROVIDER: S-EPMC6883146 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature