The Estimating effectiveness from efficacy taxonomy (EFFECT): A tool to estimate the real-world impact of health interventions.

ABSTRACT:

Aims

To develop and pilot test a taxonomy that empirically estimates health intervention effectiveness from efficacy data.

Methods

We developed a taxonomy to score health interventions across 11 items on a scale from 0-100. The taxonomy was pilot-tested in efficacy and effectiveness diabetes prevention studies identified in two separate systematic reviews; here, the face validity, inter-rater reliability and factor structure of the taxonomy were established. Random effects meta-analyses were used to obtain weight loss and diabetes incidence pooled effects across studies. These effects and taxonomy scores were used to down calibrate efficacy estimates to effectiveness estimates as follows: Efficacy effect*[Efficacy score/highest possible score].

Results

We scored 82 ef

SUBMITTER: Galaviz KI 

PROVIDER: S-EPMC6883153 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature