Marrow adipose tissue gradient is preserved through high protein diet and bed rest. A randomized crossover study.

ABSTRACT:

Context

Marrow adipose tissue (MAT) has a peripheral to central distribution in adults, higher in peripheral bones. Similarly, the spine has a caudal to cephalad MAT distribution, higher in lumbar vertebras. Diet and the level of physical activities are known modulators of MAT with significant impact on bone; however, whether these can modulate the MAT gradient is unknown.

Objective

To measure the effect of high protein diet and bed rest interventions on the lumbar MAT gradient.

Design participants intervention

In a prospective randomized crossover trial, 10 healthy men participated in 2 consecutive campaigns of 21days head-down-tilt-bed-rest (HDTBR). They received either whey protein and potassium bicarbonate-supplemented or control diet separated by a 4-month washou

SUBMITTER: Trudel G 

PROVIDER: S-EPMC6883331 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature