Predictors of Epstein-Barr virus serostatus in young people in England.

ABSTRACT: BACKGROUND:Epstein-Barr virus (EBV) is an important human pathogen which causes lifelong infection of > 90% people globally and is linked to infectious mononucleosis (arising from infection in the later teenage years) and several types of cancer. Vaccines against EBV are in development. In order to determine the most cost-effective public health strategy for vaccine deployment, setting-specific data on the age at EBV acquisition and risk factors for early infection are required. Such data are also important to inform mathematical models of EBV transmission that can determine the required target product profile of vaccine characteristics. We thus aimed to examine risk factors for EBV infection in young people in England, in order to improve our understanding of EBV epidemiology and guide fu

SUBMITTER: Winter JR 

PROVIDER: S-EPMC6883578 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature