Impact of Elagolix on Workplace and Household Productivity Among Women with Moderate to Severe Pain Associated with Endometriosis: A Pooled Analysis of Two Phase III Trials.

ABSTRACT: BACKGROUND:Endometriosis profoundly impairs women's workplace and household productivity. OBJECTIVE:The aim of this study was to evaluate the impact of elagolix on endometriosis-related workplace and household productivity losses. METHODS:Data were pooled from two phase III trials of women aged 18-49 years with moderate to severe endometriosis-associated pain treated for 6 months with elagolix 150 mg daily (QD), 200 mg twice daily (BID), or placebo. The Health-Related Productivity Questionnaire was administered at baseline, Month 3, and Month 6 to determine workplace and household absenteeism and presenteeism. Productivity changes from baseline were compared between placebo and elagolix doses via analysis of covariance. RESULTS:Workplace analyses included 1270 employed women and household

SUBMITTER: Surrey ES 

PROVIDER: S-EPMC6884431 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature