Optimizing the growth of very-low-birth-weight infants requires targeting both nutritional and nonnutritional modifiable factors specific to stage of hospitalization.

ABSTRACT:

Background

Data on how baseline characteristics, acuity, morbidity, and nutrition work in combination to affect the growth of very-low-birth-weight (VLBW, <1500 g) infants are limited.

Objective

We aimed to determine factors associated with in-hospital weight, length, and head circumference (HC) trajectories of VLBW infants.

Methods

VLBW infants (n = 316) from the GTA-DoMINO trial were included. Linear mixed-effects models assessed relations of baseline characteristics, acuity (at birth, across hospitalization), major morbidities, and nutrition (enteral feeding type, macronutrient/energy intakes) with changes in anthropometrics over hospitalization (days 1-8, 9-29, 30-75).

Results

Specific factors and the strength of their associations with growth depended on i

SUBMITTER: Asbury MR 

PROVIDER: S-EPMC6885476 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature