Downregulated Expression of hsa_circ_0005556 in Gastric Cancer and Its Clinical Significance.

ABSTRACT:

Background

Gastric cancer (GC) has a poor prognosis due to the lack of ideal tumor markers. Circular RNAs (circRNAs) are a novel type of noncoding RNA related to the occurrence of GC. Among our research, we investigated the role of hsa_circ_0005556 in GC.

Materials and methods

The expression of hsa_circ_0005556 of 100 paired GC tissues and adjacent normal tissues was detected using quantitative reverse transcription-polymerase chain reaction (qRT-PCR). A receiver operating characteristic (ROC) curve was established to evaluate the diagnostic value of hsa_circ_0005556. The correlation between the expression of hsa_circ_0005556 and corresponding clinicopathological characteristic was explored.

Results

hsa_circ_0005556 was significantly downregulated in GC tissues contra

SUBMITTER: Yang L 

PROVIDER: S-EPMC6885797 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature