Updates on the hematologic tumor microenvironment and its therapeutic targeting.

ABSTRACT: In this review article, we present recent updates on the hematologic tumor microenvironment following the 3^rd Scientific Workshop on the Haematological Tumour Microenvironment and its Therapeutic Targeting organized by the European School of Hematology, which took place at the Francis Crick Institute in London in February 2019. This review article is focused on recent scientific advances highlighted in the invited presentations at the meeting, which encompassed the normal and malignant niches supporting hematopoietic stem cells and their progeny. Given the precise focus, it does not discuss other relevant contributions in this field, which have been the scope of other recent reviews. The content covers basic research and possible clinical applications with the major therapeutic

SUBMITTER: Forte D 

PROVIDER: S-EPMC6886423 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature