Characteristics of the vaginal microbiome in cross-border female sex workers in China: a case-control study.

ABSTRACT:

Background

Female sex workers (FSWs) are key groups in the transmission of sexual transmitted infections (STI), and vaginal microbiome variations play an important role in transmission. We aimed to explore the characteristics of vaginal microbiome among FSWs.

Materials and methods

A total of 24 cross-border FSWs were randomly selected from a cross-sectional survey for female sex workers in southwest China. Thirty-seven female non-sex workers (FNSWs) were randomly selected from the gynecology clinic and health examination center. Vaginal swabs were collected, bacterial DNA extracted and 16S rRNA genes were sequenced. Differences in the vaginal microbiome between both groups were compared using bioinformatics analysis.

Results

One DNA sample was excluded due to unqualif

SUBMITTER: Hong X 

PROVIDER: S-EPMC6886492 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature