Short- and Long-term Opioid Use in Patients with Oral and Oropharynx Cancer.

ABSTRACT:

Objective

Opioid use and abuse is a national health care crisis, yet opioids remain the cornerstone of pain management in cancer. We sought to determine the risk of acute and chronic opioid use with head and neck squamous cell cancer (HNSCC) treatment.

Study design

Retrospective population-based study.

Setting

Surveillance, Epidemiology and End Results (SEER)-Medicare database from 2008 to 2011.

Subjects and methods

In total, 976 nondistant metastatic oral cavity and oropharynx patients undergoing cancer-directed treatment enrolled in Medicare were included. Opiate use was the primary end point. Univariate and multivariable logistic analyses were completed to determine risk factors.

Results

Of the patients, 811 (83.1%) received an opioid prescription dur

SUBMITTER: McDermott JD 

PROVIDER: S-EPMC6886698 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature