Clinical outcomes and mortality in old and very old patients undergoing cardiac resynchronization therapy.

ABSTRACT:

Aim

Cardiac resynchronization therapy (CRT) is a valid therapeutic option for patients with heart failure (HF). However, the elderly population was not well represented in the guidelines. The primary end point was to evaluate the impact of advanced age on clinical response and cardiovascular and total mortality of patients undergoing CRT. The secondary end point was to assess the rate of acute complications related to the procedure.

Methods and results

A total of 249 consecutive patients with HF and optimized treatment, QRS ≥ 120 ms, ejection fraction (EF) ≤ 35% and functional class (FC) III/ IV (NYHA) underwent CRT and divided into 3 groups: Group I-< 65 years-88/ 249 (35%); Group II- 65 to 75 years (old)- 72/ 249 (29%); Group III-≥ 75 years (very old)- 89/ 249 (36%). The i

SUBMITTER: Montenegro Camanho LE 

PROVIDER: S-EPMC6886771 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature