Association between disease-modifying therapies for multiple sclerosis and healthcare utilisation on a population level: a retrospective cohort study.

ABSTRACT: OBJECTIVE:Disease-modifying therapy (DMT) use in multiple sclerosis (MS) has increased significantly. However, the impact of DMTs on healthcare use is limited and conflicting, and rarely examined at a population level. This study examined the association between DMTs and healthcare utilisation at the population level. DESIGN:Retrospective cohort. SETTING:Health administrative data from Saskatchewan, Canada (1997-2016). PARTICIPANTS:To test for associations at the population level, we identified two cohorts. The general population cohort included all Saskatchewan residents ≥18 years who were drug plan beneficiaries. The MS cohort included individuals ≥18 years, identified using a validated definition (≥3 hospital, physician or drug claims for MS). MAIN OUTCOME MEASURES AND METHODS:To test f

SUBMITTER: Al-Sakran L 

PROVIDER: S-EPMC6887031 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature