Activation of NK cells in male cancer survivors by fucoidan extracted from Cladosiphon okamuranus.

ABSTRACT: Cancer survivors are highly motivated to seek information about the use of dietary supplements and complementary nutritional therapies to improve their quality of life. Fucoidan, a sulfated polysaccharide extracted from brown marine alga, exhibits a wide range of bioactivities, including anticancer activity. As natural killer (NK) cells serve an important role in defenses against tumor cells, the present study examined the effects of fucoidan extracted from Cladosiphon Okamuranus on NK cell activity in cancer survivors. A prospective, open-label clinical study was conducted on cancer survivors treated with fucoidan via oral administration; 11 cancer survivors with a performance status of 0 or 1 participated and consumed 3 g of fucoidan for 6 months. No significant changes were observed in

SUBMITTER: Nagamine T 

PROVIDER: S-EPMC6888040 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature