Adaptive current tDCS up to 4 mA.

ABSTRACT:

Background

Higher tDCS current may putatively enhance efficacy, with tolerability the perceived limiting factor.

Objective

We designed and validated electrodes and an adaptive controller to provide tDCS up to 4 mA, while managing tolerability. The adaptive 4 mA controller included incremental ramp up, impedance-based current limits, and a Relax-mode where current is transiently decreased. Relax-mode was automatically activated by self-report VAS-pain score >5 and in some conditions by a Relax-button available to participants.

Methods

In a parallel-group participant-blind design with 50 healthy subjects, we used specialized electrodes to administer 3 daily session of tDCS for 11 min, with a lexical decision task as a distractor, in 5 study conditions: adaptive 4 mA, ad

SUBMITTER: Khadka N 

PROVIDER: S-EPMC6888879 | biostudies-literature | 2020 Jan - Feb

REPOSITORIES: biostudies-literature