Dataset Information

Dairy, soy, and calcium consumption and risk of cognitive impairment: the Singapore Chinese Health Study.

ABSTRACT:

Purpose

It is unclear if midlife consumption of dairy and soy food intake, and their components of calcium and isoflavones (in soy), is related to cognitive impairment in elderly.

Methods

We used baseline data on lifestyle and habitual diet of 16,948 participants collected during their recruitment into the Singapore Chinese Health Study from 1993 to 1998, and data on their cognitive function, measured using a 30-item Singapore modified Mini-Mental State Examination, during follow-up interviews from 2014 to 2016. We used multivariable logistic regression models to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) for developing cognitive impairment.

Results

Higher dairy intake was associated with a lower risk of cognitive impairment in a dose-dependent manner (P for trend = 0.009). Compared to the lowest quartile of dairy intake, ORs (95% CIs) were 0.93 (0.81-1.07) for the second, 0.88 (0.76-1.01) for the third, and 0.82 (0.72-0.94) for the fourth quartiles of intake. Similar results were found for dairy calcium intake (P for trend = 0.008). However, there was no statistically significant association for intake of soy (OR comparing extreme quartiles 0.99, 95% CI 0.87-1.14, P for trend = 0.92), isoflavones (OR 1.01, 95% CI 0.88-1.15, P for trend = 0.90) or non-dairy calcium (OR 1.06, 95% CI 0.86-1.30, P for trend = 0.81) with risk of cognitive impairment.

Conclusions

Dairy intake at midlife could have a protective association against cognitive impairment that may not be attributed to its calcium content alone, while soy or isoflavone intake was not associated with the cognition of elderly in our study.

SUBMITTER: Talaei M

PROVIDER: S-EPMC6888923 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Publications

Dairy, soy, and calcium consumption and risk of cognitive impairment: the Singapore Chinese Health Study.

Talaei Mohammad M Feng Lei L Yuan Jian-Min JM Pan An A Koh Woon-Puay WP

European journal of nutrition 20190603 4

<h4>Purpose</h4>It is unclear if midlife consumption of dairy and soy food intake, and their components of calcium and isoflavones (in soy), is related to cognitive impairment in elderly.<h4>Methods</h4>We used baseline data on lifestyle and habitual diet of 16,948 participants collected during their recruitment into the Singapore Chinese Health Study from 1993 to 1998, and data on their cognitive function, measured using a 30-item Singapore modified Mini-Mental State Examination, during follow- ...[more]

PMID: 31161350

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Dataset Information

Dairy, soy, and calcium consumption and risk of cognitive impairment: the Singapore Chinese Health Study.

Purpose

Methods

Results

Conclusions

Publications

Dairy, soy, and calcium consumption and risk of cognitive impairment: the Singapore Chinese Health Study.

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