The integrative knowledge base for miRNA-mRNA expression in colorectal cancer.

ABSTRACT: "miRNA colorectal cancer" (https://mirna-coadread.omics.si/) is a freely available web application for studying microRNA and mRNA expression and their correlation in colorectal cancer. To the best of our knowledge, "miRNA colorectal cancer" has the largest knowledge base of miRNA-target gene expressions and correlations in colorectal cancer, based on the largest available sample size from the same source of data. Data from high-throughput molecular profiling of 295 colon and rectum adenocarcinoma samples from The Cancer Genome Atlas was analyzed and integrated into our knowledge base. The objective of developing this web application was to help researchers to discover the behavior and role of miRNA-target gene interactions in colorectal cancer. For this purpose, results of differential exp

SUBMITTER: Jevsinek Skok D 

PROVIDER: S-EPMC6889159 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature