Dataset Information

Positive urgency partially mediates the relationship between childhood adversity and problems associated with substance use in an undergraduate population.

ABSTRACT:

Background

Childhood adversity predicts the development of substance use problems in young adulthood. Building on past work examining the mediating role of impulsivity in the relationship between childhood maltreatment and substance use in alcohol and nicotine users, this study examined the relationship with other substances in a representative undergraduate sample. In addition, the study aimed to determine whether there was convergence in findings between different measures of childhood adversity and impulsivity.

Method

309 undergraduate students completed self-report questionnaires assessing childhood adversity (Childhood Trauma Questionnaire - CTQ; Adverse Childhood Experience Scale - ACE), impulsivity (Short UPPS-P; Barratt Impulsivity Scale - BIS-11) and problems associated with substance use (Drug Abuse Screening Test - DAST-10).

Results

The SUPPS-P positive urgency facet partially mediated the relationship between CTQ and DAST-10 (b = 0.0039, 95% CI [0.0008, 0.0086]), as well as between ACE and DAST-10 (b = 0.015, 95% CI [0.0014, 0.0446]). The BIS-11 motor facet partially mediated the effect of CTQ on DAST-10 (b = 0.0017, 95% CI [0.0002, 0.0054]).

Conclusion

Positive urgency partially mediated the relationship between childhood maltreatment and substance use problems for both the CTQ and ACE. While these results are consistent with past studies showing a selective mediation effect of positive urgency in a sample of young adults, they are inconsistent with those showing a selective mediation effect of negative urgency in a sample of heavy drinkers. Together, these findings suggest that the relationship between childhood adversity, impulsivity, and substance use-related problems may be influenced by experience.

SUBMITTER: Ramakrishnan N

PROVIDER: S-EPMC6889254 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Positive urgency partially mediates the relationship between childhood adversity and problems associated with substance use in an undergraduate population.

Ramakrishnan Nayani N McPhee Matthew M Sosnowski Alexandra A Rajasingaam Vinitaa V Erb Suzanne S

Addictive behaviors reports 20191018

<h4>Background</h4>Childhood adversity predicts the development of substance use problems in young adulthood. Building on past work examining the mediating role of impulsivity in the relationship between childhood maltreatment and substance use in alcohol and nicotine users, this study examined the relationship with other substances in a representative undergraduate sample. In addition, the study aimed to determine whether there was convergence in findings between different measures of childhood ...[more]

PMID: 31828206

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Project description:IntroductionParental suicide attempts and suicide death increase suicide risk in their offspring. High levels of impulsivity have been observed in families at high risk for suicide. Impulsivity, a highly heritable trait that is especially elevated in childhood, is frequently measured with the UPPS-P Impulsive Behavior Scale, which includes negative urgency, positive urgency, sensation seeking, premeditation, and perseverance. Our study examined the association between the UPPS-P facets and suicide ideation (without suicide attempts) and suicide attempts at baseline and first-time endorsement within the next two years in childhood. We also examined how the UPPS-P facets mediated the association between parental suicide attempts and suicide death and offspring first-time suicide ideation and attempts at follow-up.MethodsThe sample was 9,194 children (48.4% female; 9-10 years old) from the Adolescent Brain Cognitive Development (ABCD) study, assessed yearly three times. At Time 1 (T1), caregivers reported on suicide attempts and suicide deaths (combined) of the biological parents. Caregivers and children reported on suicide ideation and attempts in the KSADS-PL DSM-5 at each time point, T1 and follow-up (T2 and/or T3). The Short UPPS-P Scale (child-report) assessed the impulsivity facets at T1, which were computed as latent variables.ResultsAt T1, 6.7% of children had a parent who had attempted or died by suicide. Most UPPS-P facets were associated with suicide ideation and attempts at T1 and T2/T3. In adjusted models, parental suicide attempts and suicide death were associated with offspring negative and positive urgency. In mediation models, parental suicide attempts and suicide death had an indirect effect on offspring first-time suicide ideation at T2/T3 through negative urgency (OR = 1.04; 95% CI, 1.01-1.08) and positive urgency (OR = 1.03, 95% CI, 1.01-1.05). Similar results were found for first-time suicide attempts at T2/T3.DiscussionOur findings support an impulsive pathway in the familial transmission of suicide risk. For all youth, interventions that target multiple UPPS-P facets may help prevent or reduce suicide risk. For offspring whose parents have attempted or died by suicide, clinicians should pay particular attention to children who impulsively act on extreme emotions, as they may be at higher suicide risk.

Project description:This study introduced the novel concept of Centeredness, a measure of the emotional atmosphere of the family of origin and a target adult individual's perception of feeling safe, accepted, and supported from childhood primary caregivers and other family members. This study developed a Centeredness scale for adult respondents and tested hypotheses that higher levels of overall Centeredness would predict lower levels of depression and anxiety symptoms; suicidal thoughts and behaviors (STBs); and aggressive behavior; and higher levels of life satisfaction. Predictive effects of Centeredness were compared against attachment-related anxiety and avoidance, and adverse and benevolent childhood experiences (ACEs and BCEs). Participants were recruited via the Prolific-Academic (Pro-A) survey panel into two large independent samples of US young adults aged 19-35 years [Sample 1 (test sample), N = 548, 53.5% female, 2.2% gender non-conforming, 68.3% White, recruited before the pandemic; Sample 2 (replication sample), N = 1,198, 56.2% female, 2.3% gender non-conforming, 66.4% White; recruited during the pandemic]. Participants completed the novel Centeredness scale, which showed strong psychometric properties, and standardized, publicly available assessments of childhood experiences and mental health outcomes. Centeredness was the only variable that significantly predicted each mental health outcome across both samples. BCEs predicted all outcomes except aggressive behavior in the test sample. Centeredness and BCEs were also the only two variables that significantly predicted a dimensional mental health composite in both samples. Neither attachment-related anxiety and avoidance nor ACEs were as broadly predictive. The Centeredness scale assesses emotional aspects of childhood family relationships with individuals of diverse backgrounds and family compositions. Clinical and cultural implications are discussed.Supplementary informationThe online version contains supplementary material available at 10.1007/s42844-023-00089-x.

Dataset Information

Positive urgency partially mediates the relationship between childhood adversity and problems associated with substance use in an undergraduate population.

Background

Method

Results

Conclusion

Publications

Positive urgency partially mediates the relationship between childhood adversity and problems associated with substance use in an undergraduate population.

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