Metabolic shift induced by synthetic co-cultivation promotes high yield of chain elongated acids from syngas.

ABSTRACT: Bio-catalytic processes for sustainable production of chemicals and fuels receive increased attention within the concept of circular economy. Strategies to improve these production processes include genetic engineering of bio-catalysts or process technological optimization. Alternatively, synthetic microbial co-cultures can be used to enhance production of chemicals of interest. It remains often unclear however how microbe to microbe interactions affect the overall production process and how this can be further exploited for application. In the present study we explored the microbial interaction in a synthetic co-culture of Clostridium autoethanogenum and Clostridium kluyveri, producing chain elongated products from carbon monoxide. Monocultures of C. autoethanogenum converted CO to acetat

SUBMITTER: Diender M 

PROVIDER: S-EPMC6889307 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature