Elimination of hepatitis C virus in Germany: modelling the cost-effectiveness of HCV screening strategies.

ABSTRACT:

Background

Chronic hepatitis C is a major public health burden. With new interferon-free direct-acting agents (showing sustained viral response rates of more than 98%), elimination of HCV seems feasible for the first time. However, as HCV infection often remains undiagnosed, screening is crucial for improving health outcomes of HCV-patients. Our aim was to assess the long-term cost-effectiveness of a nationwide screening strategy in Germany.

Methods

We used a Markov cohort model to simulate disease progression and examine long-term population outcomes, HCV associated costs and cost-effectiveness of HCV screening. The model divides the total population into three subpopulations: general population (GEP), people who inject drugs (PWID) and HIV-infected men who have sex with me

SUBMITTER: Krauth C 

PROVIDER: S-EPMC6889318 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature