Complete atrioventricular block due to timolol eye drops: a case report and literature review.

ABSTRACT:

Background

Timolol Maleate is a non-selective beta-adrenergic blocker that is commonly used to treat open-angle glaucoma. Despite its topical administration, ophthalmic timolol enters systemic circulation and produces a systemic beta-adrenergic blockade. We report a case of long-term timolol use that uncovered and worsened an underlying cardiac conduction defect demonstrated as a third degree atrioventricular (AV) block.

Case presentation

A 62-year old male with a 13-year history of glaucoma was hospitalized due to shortness of breath, dizziness, and amaurosis. Electrocardiography indicated a heart rate (HR) of 29 bpm with complete atrioventricular (AV) block, and the HR was significantly increased with the treatment of isoprenaline. However, the patient experienced bradycar

SUBMITTER: Wang Z 

PROVIDER: S-EPMC6889336 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature