Cardiovascular risk factors and memory decline in middle-aged and older adults: the English Longitudinal Study of Ageing.

ABSTRACT:

Background

We investigated the association between trajectories of verbal episodic memory and burden of cardiovascular risk factors in middle-aged and older community-dwellers.

Methods

We analysed data from 4372 participants aged 50-64 and 3005 persons aged 65-79 years old from the English Longitudinal Study of Ageing who were repeatedly evaluated every 2 years and had six interviews of a 10-year follow-up. We measured the following baseline risk factors: diabetes, hypertension, smoking, physical inactivity and obesity to derive a cardiovascular risk factor score (CVRFs). Adjusted linear mixed effect regression models were estimated to determine the association between number of CVFRs and six repeated measurements of verbal memory scores, separately for middle-aged and older

SUBMITTER: Olaya B 

PROVIDER: S-EPMC6889660 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature