Early detection of heart function abnormality by native T1: a comparison of two T1 quantification methods.

ABSTRACT:

Objective

To compare the robustness of native T1 mapping using mean and median pixel-wise quantification methods.

Methods

Fifty-seven consecutive patients without overt signs of heart failure were examined in clinical routine for suspicion of cardiomyopathy. MRI included the acquisition of native T1 maps by a motion-corrected modified Look-Locker inversion recovery sequence at 1.5 T. Heart function status according to four established volumetric left ventricular (LV) cardio MRI parameter thresholds was used for retrospective separation into subgroups of normal (n = 26) or abnormal heart function (n = 31). Statistical normality of pixel-wise T1 was tested on each myocardial segment and mean and median segmental T1 values were assessed.

Results

Segments with normally di

SUBMITTER: Triadyaksa P 

PROVIDER: S-EPMC6890701 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature